Although PrEP has been recommended by WHO since 2015, implementation in Latin America has been limited. This symposium will take stock of current advances and lessons learned in the implementation of PrEP in Latin America, highlighting successful approaches, enabling factors and challenges to scale-up and why PrEP could be an important addition to efforts to reach epidemic control in the region. The session will present experiences from the ImPrEP project in Brazil, Mexico and Peru and discuss challenges in reaching vulnerable MSM and TGW, particularly the younger and lower incomes populations; debate strategies for improving PrEP continuation; present data on the need for STI screening and treatment; analyze successful strategies and innovations for reaching, enrolling and retaining TGW, highlight community perspectives on engagement and demand creation for PrEP services; and examine the specific socio-economic regional landscape on PrEP-drugs, such as regulatory issues, patents and costing. This symposium

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